Везде

RAS Chemistry & Material ScienceХимическая физика Advances in Chemical Physics

  • ISSN (Print) 0207-401X
  • ISSN (Online) 3034-6126

Study of fluorescence quenching by bilirubin of carbocyanine dye in complex with DNA. Effect of Cu2+ additives

You can
PII
305187-690178-1
DOI
10.7868/30178-1
Publication type
Article
Status
Published
Authors
P. G. Pronkin
  • Affiliation: Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Volume/ Edition
Volume 44 / Issue number 6
Pages
43-54
Abstract
The effect of bilirubin on the spectral fluorescence properties of the cationic thiacarbocyanine dye Cyan 2 in the presence of DNA was studied. The Cyan 2 dye forms a non-covalent complex with DNA, which leads to an increase in the fluorescence of the dye. Interaction with bilirubin leads to effective quenching of dye fluorescence in complex with DNA (static mechanism), which can be used to construct a spectral-fluorescent sensor for bilirubin. The results of in vitro experiments are illustrated by in silico molecular docking experiments. The effect of Cu2+ ion additives can further enhance the quenching of dye fluorescence by bilirubin. Effective quenching constants and detection limits of bilirubin using the Cyan 2–DNA system (LOD and LOQ) are determined.
Keywords
тиакарбоцианиновый краситель ДНК комплексообразование билирубин спектрально-флуоресцентные зонды тушение флуоресценции
Date of publication
16.06.2025
Year of publication
2025
Number of purchasers
0
Views
89

References

  1. 1. Pronkin P.G., Tatikolov A.S. // Molecules. 2022. V. 27. No. 19. P. 6367. https://doi.org/10.3390/molecules27196367
  2. 2. Татиколов А.С., Пронкин П.Г., Шведова Л.А., Панова И.Г. // Хим. физика. 2019. Т. 38. № 12. С. 11. https://doi.org/10.1134/S0207401X19120185
  3. 3. Kim S.Y., Park S.C. // Front. Pharmacol. 2012. V. 3, P. 45. https://doi.org/10.3389/fphar.2012.00045
  4. 4. Татиколов А.С., Панова И.Г. // Хим. физика. 2024. T.43. № 11. С. 3. https://doi.org/10.1134/S1990793124701173
  5. 5. Soto Conti C.P. // Arch. Argent. Pediatr. 2021. V. 119. No. 1. e18. https://doi.org/10.5546/aap.2021.eng.e18
  6. 6. Tatikolov A.S., Pronkin P.G., Panova I.G. // Biophys. Chem. 2025. V. 318. P. 107378. https://doi.org/10.1016/j.bpc.2024.107378
  7. 7. Singla N., Ahmad M., Mahajan V., Singh P., Kumar S. // Sens. Diagn. 2023. V. 2. P. 1574. http://dx.doi.org/10.1039/D3SD00157A
  8. 8. Karmakar S., Das T.K., Kundu S., Maiti S., Saha A. // ACS Appl. Bio Mater. 2020. V. 3. P. 8820. https://doi.org/10.1021/acsabm.0c01165
  9. 9. Xiao W., Liu J., Xiong Y. et al. // Anal. Bioanal. Chem. 2021. V. 413. P. 7009. https://doi.org/10.1007/s00216-021-03660-6
  10. 10. Speck, W., Behrman, R. // Pediatr. Res. 1974. V. 8. P. 451. https://doi.org/10.1203/00006450-197404000-00665
  11. 11. Velapoldi R.A., Menis O. // Clinical Chem. 1971. V. 17. No. 12. P. 1165. PMID: 5118155
  12. 12. Asad S.F., Singh S., Ahmad A., Hadi S.M. // Biochim. Biophys. Acta. 1999. V. 1428. No. 2–3. P. 201. https://doi.org/10.1016/s0304-4165 (99)00075-6
  13. 13. Asad S.F., Singh S., Ahmad A., Hadi S.M. // Toxicology Lett. 2002. V. 131. № 3. P. 181. https://doi.org/10.1016/s0378-4274 (02)00031-0
  14. 14. Акимкин Т.М., Татиколов А.С., Ярмолюк С.М. // Химия высоких энергий. 2011. Т. 45. № 3. С. 252.
  15. 15. Yarmoluk S.M., Lukashov S.S., Losytskyy M.Y., Akerman B., Kornyushyna O.S. // Spectrochim. Acta. Part A. 2002. V. 58. No. 14. P. 3223. https://doi.org/10.1016/S1386-1425 (02)00100-2
  16. 16. Xu C., Losytskyy M.Y., Kovalska V.B., Kryvorotenko D.V. et al. // J. Fluoresc. 2007. V. 17. P. 671. https://doi.org/10.1007/s10895-007-0215-z
  17. 17. Tatikolov A.S., Akimkin T.M., Pronkin P.G., Yarmo­luk S.M. // Chem. Phys. Lett. 2013. V. 556. P. 287. https://doi.org/10.1016/j.cplett.2012.11.097
  18. 18. Mukerjee P., Ostrow J.D., Tiribelli C. // BMC Biochemistry. 2002. V. 3. P. 17. https://doi.org/10.1186/1471-2091-3-17
  19. 19. Baguley B.C., Falkenhaug E.M. // Nucl. Acids Res. 1978. V. 5. No. 1. P. 161. https://doi.org/10.1093/nar/5.1.161
  20. 20. Lakowicz J.R. Principles of Fluorescence Spectroscopy, 3rd ed. Springer, 2006.
  21. 21. ISBN: 978-0-387-31278-1
  22. 22. Hubaux A., Vos G.// Anal. Chem. 1970. V. 42. No. 8. P. 849. https://doi.org/10.1021/ac60290a013
  23. 23. MacDougall D., Crummett W.B. et al. // Anal. Chem. 1980. V. 52. P. 2242. https://doi.org/10.1021/ac50064a004
  24. 24. Valdes-Tresanco M.S., Valdes-Tresanco, M.E., Valiente, P.A., Moreno E. // Biol. Direct. 2020. V. 15. P. 12. https://doi.org/10.1186/s13062-020-00267-2
  25. 25. Drew H.R., Wing R.M., Takano T. et al. // Proc. Natl. Acad. Sci. USA. 1981. V. 78. P. 2179. https://doi.org/10.1073/pnas.78.4.2179
  26. 26. Dautant A., Langlois d’Estaintot B., Gallois B., Brown T., Hunter W.N. // Nucl. Acids Res. 1995. V. 23. P. 1710. https://doi.org/10.1093/nar/23.10.1710
  27. 27. Yang Z., Lasker K., Schneidman-Duhovny D. et al. // J. Struct. Biol. 2012. V. 179. P. 269. https://doi.org/10.1016/j.jsb.2011.09.006
  28. 28. Hanwell M.D., Curtis D.E., Lonie D.C. et al. // J. Cheminformatics. 2012. V. 4. P. 1. https://doi.org/10.1186/1758-2946-4-17
  29. 29. Пронкин П.Г., Шведова Л.А., Татиколов А.С. // Хим. физика. 2024. Т. 43. № 3. С. 3. https://doi.org/10.31857/S0207401X24030016
  30. 30. Пронкин П.Г., Татиколов А.С. // Химия высоких энергий. 2009. Т. 43. №. 6. С. 527.
  31. 31. Пронкин П.Г., Татиколов А.С. // Химия высоких энергий. 2011. Т. 45. №. 2. С. 169.
  32. 32. Пронкин П.Г., Татиколов А.С. // Хим. физика. 2021. T. 40. № 2. C. 3. https://doi.org/10.31857/S0207401X2102014X
  33. 33. Пронкин П.Г., Татиколов А.С. // Хим. физика. 2022. T. 41. № 2. С. 3. https://doi.org/10.31857/S0207401X22020091
  34. 34. Yarmoluk S.M., Lukashov S.S., Ogul’chansky T.Y., Losytskyy M.Y., Kornyushyna O.S. // Biopolym. (Biospectrosc.). 2001. V. 62. P. 219. https://doi.org/10.1002/bip.1016
  35. 35. Galhano J., Marcelo G.A., Santos H.M. et al. // Chemosensors. 2022. V. 10. P. 80. https://doi.org/10.3390/chemosensors10020080
  36. 36. Hanmeng O., Chailek N., Charoenpanich A. et al. // Spectrochim. Acta, Part A. 2020. V. 240. P. 118606. https://doi.org/10.1016/j.saa.2020.118606
  37. 37. Chen X., Nam S.W., Kim G.H. et al. // Chem. Commun. 2010. V. 46. No. 47. P. 8953. http://dx.doi.org/10.1039/C0CC03398G
  38. 38. Li J., Ge J., Zhang Z. et al. // Sens. Actuators, B. 2019. V. 296. P. 126578. https://doi.org/10.1016/j.snb.2019.05.055
  39. 39. Krishna R.M., Gupta S.K. // Bull. Magn. Res. 1994. V. 16. No. 3. P. 239.
  40. 40. Taniguchi M., Lindsey J.S. // J. Photochem. Photobiol. C. 2023. V. 55. P. 100585. https://doi.org/10.1016/j.jphotochemrev.2023.100585
  41. 41. Ghosh D., Chattopadhyay N. // J. Lumin. 2015. V. 160. P. 223. https://doi.org/10.1016/j.jlumin.2014.12.018
  42. 42. Achyuthan K.E., Bergstedt T.S., Chen L. et al. // J. Mater. Chem. 2005. V. 15. No. 27–28. P. 2648. https://doi.org/10.1016/10.1039/b501314c
  43. 43. Полетаев А.И. // Хим. физика. 2023. Т. 42. № 9. C. 74. https://doi.org/10.31857/S0207401X23090091
  44. 44. Терешкин Э.В., Терешкина К.Б., Лойко Н.Г., Коваленко В.В., Крупянский Ю.Ф. // Хим. физика. 2024. Т. 43. № 12. C. 84.
  45. 45. Разумов В.Ф. // Хим. физика. 2023. T. 42. № 2. С. 14. https://doi.org/10.31857/S0207401X23020139
QR
Translate

Индексирование

Scopus

Scopus

Scopus

Crossref

Scopus

Higher Attestation Commission

At the Ministry of Education and Science of the Russian Federation

Scopus

Scientific Electronic Library